New Zygomycete phylome: the human pathogen Lichtheimia corymbifera



PhylomeDB extends its repertoire of fungal phylomes with that of a genome of a poorly sample clade, that of the basal group zygomycetes. In this case the phylome (phylome 245) of the human pathogenic mucorales Lichtemia corymbifera has served to reveal extensive past gene duplications in this group. Lichtheimia species are the second most important cause of mucormycosis in Europe. The sequencing of its genome and the comparison with other Zygomycete species, particularly of Rhizopus delemar, the main cause of mucormycosis in Europe, has revealed specific adaptations in each of the lineages. Lichteimia, presents a high number of gene duplications that are attributable to segmental duplications. The availability of the phylome has enabled to trace and provide a relative timing of the duplications events in this group. You can browse the phylome and find more information in the associated publication:

Schwartze et. al. 2014. Gene Expansion Shapes Genome Architecture in the Human Pathogen Lichtheimia corymbifera: An Evolutionary Genomics Analysis in the Ancient Terrestrial Mucorales (Mucoromycotina) PLOS Genetics. 14(10)8