Welcome to PhylomeDB 4!

PhylomeDB is a public database for complete catalogs of gene phylogenies (phylomes). It allows users to interactively explore the evolutionary history of genes through the visualization of phylogenetic trees and multiple sequence alignments. Moreover, phylomeDB provides genome-wide orthology and paralogy predictions which are based on the analysis of the phylogenetic trees. The automated pipeline used to reconstruct trees aims at providing a high-quality phylogenetic analysis of different genomes, including Maximum Likelihood tree inference, alignment trimming and evolutionary model testing.

PhylomeDB includes also a public download section with the complete set of trees, alignments and orthology predictions, as well as a web API that faciliates cross linking trees from external sources. Finally, phylomeDB provides an advanced tree visualization interface based on the ETE toolkit, which integrates tree topologies, taxonomic information, domain mapping and alignment visualization in a single and interactive tree image. 

What's new in phylomeDB 4?


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September 17, 2017 - 09:57


We live in a universe that is very hostile to life as we know, and human life is particularly fragile. We can survive sheltered in a small range of pressure of a mix of gases with a particular composition, ensuring a proper balance between molecular oxygen and chemically inert gases such as molecular nitrogen. We need to take care also to keep ourselves within certain...

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