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Sep
14
2010

The pea aphid genome is the first to be annotated using a comprehensive phylogeny-based approach

By tgabaldon

Within the context of the sequencing of the genome of the pea aphid, Acyrthosiphon pisum, we undertook a phylogenetic analysis for every protein of this species. The resulting phylome includes the evolutionary relationships of all predicted aphid proteins and their homologues among 13 other fully-sequenced arthropods and three out-group species. Subsequent analyses have revealed multiple gene expansions that are specific to aphids and may provide hints on adaptations to a particular diet and developmental biology. Phylogeny-based orthology have served to reliably transfer functional annotations to 4058 pea aphid genes that display one-to-one orthology relationships with Drosophila melanogaster annotated genes.


 
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